Membranolytic Activity of Bile Salts: Influence of Biological Membrane Properties and Composition
The two main steps of the membranolytic activity of detergents: 1) the Bedroom Package partitioning of detergent molecules in the membrane and 2) the solubilisation of the membrane are systematically investigated.The interactions of two bile salt molecules, sodium cholate (NaC) and sodium deoxycholate (NaDC) with biological phospholipid model membr